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Flora and Vegetation of Asian Russia

2025 year, number 3

ASTRAGALUS GLYCYPHYLLOS (FABACEAE): BIOLOGICALLY ACTIVE SUBSTANCES, PHARMACOTHERAPEUTIC ACTIVITY AND BENEFICIAL PROPERTIES, USE IN PHARMACY AND MEDICINE (REVIEW)

Irina E. Lobanova
Central Siberian Botanical Garden SB RAS, Novosibirsk, Russia
Keywords: Fabaceae, Astragalus glycyphyllos, chemical composition, antihypertensive, antibiotic, antioxidant, antitumor, neuroprotective activity

Abstract

A review of the scientific literature devoted to the study of Astragalus glycyphyllos in various biological and chemical aspects are presented. Currently, studies of the native chemical complex of this type of Astragalus are relevant, with the establishment of the structure of its components, pharmacotherapeutic activity, useful properties and potential uses of A. glycyphyllos not only as a model object in biomedical research, but also, for the conditions of Russia, as analogues of pharmacopoeial types of Astragalus. The results obtained by scientists from different countries, as well as the experience of using A. glycyphyllos in folk medicine from different countries, serve as the basis for the multipurpose use of raw materials of this type of astragalus in pharmacy and medicine. Currently, studies of the recently established neuroprotective activity of extracts and individual compounds of the native A. glycyphyllos complex as potential drugs for the treatment of certain neurodegenerative diseases are becoming particularly relevant.