On the Impact of Flow-Diverters on the Hemodynamics of Human Cerebral Aneurysms
D. V. Parshin1,2, Yu. O. Kuyanova1,2, D. C. Kislitsin3, U. Windberger4, A. P. Chupakhin1,2
1Lavrent'ev Institute of Hydrodynamics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090, Russia
2Novosibirsk National Research State University, Novosibirsk, 630090, Russia
3Meshalkin National Medical Research Center, Novosibirsk, 630055, Russia
4Center for Biomedical Research, Vienna, 1090, Austria
Keywords: церебральная аневризма, потокперенаправляющий стент, гемодинамика мозга, реконструкция DICOM-изображений, неньютоновская реология крови, cerebral aneurysm, flow-diverter, brain hemodynamics, reconstruction of DICOM images, non-Newtonian blood rheology
Abstract
The impact of flow-diverters used in the treatment of cerebral aneurysm on human brain hemodynamics was evaluated qualitatively and quantitatively. Numerical simulation of flow-diverter placement in cerebral vessels with aneurysms for the case history of a real patient was carried out with the commercial ANSYS 17.2 package, using different (Newtonian and non-Newtonian) hydrodynamic models of blood rheology in different parts of the vessel and aneurysm, according to experimental data. It is shown that after flow-diverter placement, the blood flow through the artery segment containing the aneurysm neck decreases, resulting in a redistribution of the cerebral blood flow, which becomes close to a healthy bloodstream. Changes in wall tangential stresses in the flow-diverter region are indicative of possible aneurysm recanalization.
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