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With acid-base indicators, the change in functional composition of surface of calcite, fluorite and scheelite under the action of high-voltage nano-second pulses has been analyzed. After impulse treatment of mineral samples for t ≤ 50 s, the concentration of electron-donor Lewis (рКа = - 4.4) and proton-donor (рКа = 1.3, рКа = 4.1) Brønsted centers has grown on the surface of calcite. It is shown in the article that basic transformations of fluorite and scheelite surface under pulse treatment are connected with mutual transformations of Lewis bases and Brønsted acids.

The authors evaluate the ratio of activities exhibited by physical and chemical adsorptions of an agent on sulfide minerals. The following assumptions are made: 1) the main kinetic restriction for flotation contact (particle-bubble interaction) is the film between mineral particle and air bubble; 2) water is removed from the film by both physical and chemical adsorptions; 3) the water volume removed by physical adsorption is conditioned by the difference in the volumes of water in the films bounded by meniscuses with advancing angle Θ _A and receding angle Θ _R and neck radius R. The water volume removed under the action of surface forces (hydrophobic, dispersive) was disregarded as the agent attachment was low dense and mosaic. The article reports experimental data on limit values of static advancing and receding angles on the surface of some sulfide metals. It is shown that selectivity of flotation of sulfides depends on the ratio of water volumes removed from the film by desorbable physical adsorption and non-desorbable chemical adsorption types of agents. The proposed method of selectivity estimation is suitable for minerals with similar (close) properties of the surface when stabilizing ion-electrostatic interaction between minerals and air bubbles is absent or insignificant. The calculation results may be of use to optimizing collecting ability of physically adsorbed low-polar or desorbable derivants of ionized agent with intent to improve selectivity of separation of sulfide minerals.

The authors have analyzed copper adsorption at manganese ore from Porozhinsky province. The results allow a hypothesis on the mechanisms of adsorption kinetics: adsorption rate is limited both by diffusion processes and by chemical interaction. The analysis of adsorption isotherm and its mathematical processing show that copper exhibits strong affinity toward manganese ore surface; the Langmuir equation describes the copper adsorption equilibrium with high correlation factor. The Gibbs energy has negative value.

There is sufficient experimental database thus far collected on structural and chemical changes in minerals with different types of chemical bonding under activation grinding. The research has shown the possibility to predict specifics of grinding and defect formation in minerals with different types of chemical bonding. The article shows that type and number of defects formed on the surface of minerals govern important processing properties of the minerals such as capacities to be hydrated, dissolved, floated etc.

The authors offer a new approach to processing seismological reports using Voronoi diagrams to detect clustered dynamic events in an area exposed to high production loading, implemented as a cloud service in the framework of geomechnical-geodynamic safety system of Kuzbass. The cloud service allows pre-processing of array of seismic events prior to computation of migration trajectories of reduced seismic energy release centers according to Oparin, which greatly improves computation accuracy. The article reports the results of seismicity assessment for the Kemerovo Region using the chain of services “Voronoi diagram-migration trajectories of reduced seismic energy release centers”.

The article considers the method of recovering structural integrity of operating degassing wells without outage and the scheme of cross-wise hydraulic fracturing in well bottom zone using mechanical anchor. Advantages of the scheme with anchor are discussed as against directional fracturing with a slot initiator. The technical solutions on protection of methane drainage zone from air leaks from underground excavations are presented.

Results of design and analysis of system for haulage of equipment in uncased boreholes drilled from underground excavations are reported. A thruster is a pneumatic percussion device. The optimal parameters of the haulage system operation in various conditions are determined. Using mathematical description of movement of thruster in well, the authors derive relations for the thruster velocity as a function of various initial data.

This article deals with the implementation possibilities and prospects of the activity approach in social philosophy in the context of post-non-classical type of scientific rationality. It actualizes the axiological perspective. The categories of «sociality», «activity», «subject activity», «collective activity» are analyzed from this position; their content reveals the idea of developing all forms of public life and the person through active human nature as its generic essence. The author analyzes the ideas of modern social philosophy in the context of the interpretation of «sociality» as a poly-subject activity and mental activity approach, where the key to the use of the definition of «activity» is in the axiological perspective of goal-setting, realization and achievement activity. It is concluded that the problem of the activity-related relativity is connected with resolving the issues of personal identity and its anthropological authenticity as the rootedness of the person in the system of values of his/her nation. In the Russian context it can be productively resolved by incorporation of the ideas of Russian religious philosophy in the modern scientific knowledge. It is summarized that the activity approach currently aspires to become one of the leading explanatory principles in analysis, description, design and forecasting of social processes and social structures in postclassical rationality. It gives the opportunity to explore the social reality in accordance with axiological attitudes of a particular society. The implementation of the activity approach not only enriches the research base of social philosophy, allows realizing its recommendation and prognostic functions, but also provides an opportunity to design, to create social reality that is seen as extremely important in the conditions of globalization and transformation of values.

The work was devoted to studying the content of hemoglobin complexes, the level of energy-rich compounds, their relationship with the viscoelastic parameters of red blood cells in patients with resistant hypertension to identify possible pathogenetic features of the disease. Analysis of the processes have carried out on the basis of the methods of Raman spectroscopy (Raman), Nuclear Magnetic Resonance spectroscopy (NMR) and the method of Dielectrophoresis of erythrocytes (DEF) in a Non-Uniform Alternating Electric Field - effective, sensitive, non-destructive methods of investigation of different environments, proven in studies biological objects. Studies conducted in erythrocytes groups of subjects with arterial hypertension, including - resistant (42 people) and a comparison group (23 persons). The observed reduction in reserves of nitric oxide inside red blood cells, reducing its bioavailability associated with changes in the level and composition of intracellular energy compounds, viscoelastic parameters of red blood cells are probably one of the pathogenetic factors for the development of resistant hypertension and target for therapeutic intervention.

The aim of research: the studying of blood lipid spectrum, C-reactive protein concentration, and free circulating mitochondrial DNA changes in the course of aorta atherosclerosis development in early steps of high-cholesterol diet in experiment. Material and methods. Dyslipidemia was induced by high-cholesterol diet in rabbits “Chinchilla”. The C-reactive protein level and lipid spectrum was analyzed with Beckman synhron 4 multianalyzer (Beckman coulter, USA). The mitochondrial DNA level was registered by real-time PCR. The ultra structure of aorta surface was studied by scanning electron microscopy. Results. It was shown that in the blood of experimental animals is formed the Beckman imbalance of atherogenic and antiatherogenic cholesterol fractions (on 2 days of dyslipidemia) and iselevated the C-reactive protein level (on the 8 days). Concurrently, on the 16 days of study, we registered the leucocyte adhesion on the aorta surface in the areas of connections with arteria, which could be focuses of atherosclerotic plaque development. The level of free circulating mitochondrial DNA showed the tendency to 3-fold elevation in comparing with control. However, this data predetermined the prospects of blood plasma mitochondrial DNA level studying on the more late stages of dyslipidemia. Conclusion. In the whole, the detected complex of biochemical disturbances of blood and ultrastructural changes of aorta surface in the course of early steps of high-cholesterol diet maybe prospective model of early events of atherosclerosis for pre-clinical translational research in the development of new technologies for diagnostics, prophylaxis, and treatment of lipid metabolism disturbances and atherosclerosis.